@Frederick60, what do you hope to achieve in going the 16 tooth front sprocket route?
You have not provided any info on your riding style or the type of roads that you ride the most.
FWIW, my 1st gen K5 Wee has a 14F/47R sprocket combo, which is really great for slow manuvers, easy to pull off from a stop when in low moving traffic, better when riding in hilly country, feels more powerful when riding into strong head wind and much better when off the black top. The gear ratios are a bit quicker so one changes up quicker. When at highway speeds the rpm is slightly higher but then the Wee is not shy in running at higher rpms.
I did find that the fuel consumption seems to increase when riding above the 6,000 rpm for extended periods. Maybe your newer model is more forgiving.
My K6 Wee on the other hand has a 16F/45R sprocket combo for a more relaxed / lower rpm / less buzz ride at riding at highway speeds, but I find that I need to ride / slip the clutch when pulling off on most inclines, plus when riding in slow / busy traffic. On the K6 I find that I seldom end up in 6th gear when in city traffic speed limits, as the rpms are sometimes too low for any useful pulling power when riding at the 60 km/h limits.