At the end of the day they are 50/50 tyres.
They will not have the same levels of grip as a pure road tyre like a PR4's, Anakee 3's or A40's.
The Beemer boys have been running the simular TKC80's for years now and one of the things you learn with the TKC it to use the throttle sparingly in the wet. I had a few slides with them and that was only with a 250cc trail bike.
The Wee and the Varadero had no serious issues with either the K60's or the E-07.
Though I did find the K60 rear was more likey to lock is you stamp on the rear brake than E-07 on the Wee. (Varadero has linked brakes so never showed this tendancy)
At the end of the day K60's E-07 and TKC80 are for rough road, farm tracks, fire roads and looking the part at Starbucks.
If your not riding roads that require or may require them you need a road tyre like the A40' or Anakee 3's or PR4's. They will last longer and give a better ride on the road.
I like to ride a lot of single track roads in the country and go ventureing down lanes I have no idea where they lead or what the surface will be like. A 50/50 tyre gives me the confidence to do this kind of riding.
Currently running A40 Adventures and Roadtec 01's before that and they give me great road holding and confidence on the main roads but the lack of blocky-ness stops me venturing down the unknown lanes.
Next set of tyres will be Mitas E-07 - and they are the only sodding tyre I can't get in work from any of our suppliers.